Does Rheumatoid Arthritis Really Improve During Pregnancy? A Systematic Review and Metaanalysis.
J Rheumatol
; 46(3): 245-250, 2019 03.
Article
em En
| MEDLINE
| ID: mdl-30385703
ABSTRACT
OBJECTIVE:
We performed a systematic review and metaanalysis to assess rheumatoid arthritis (RA) disease activity during pregnancy using objective disease activity scoring systems.METHODS:
A systematic review of PubMed, EMBASE/Medline, Cochrane, and LactMed databases was performed. Our inclusion criteria for analysis were prospective studies, more than 5 patients per study, and data on RA using an objective scoring system conducted by a clinician/health professional.RESULTS:
Ten studies were eligible for final analysis, which included 237 patients, of which prepartum data were available for 204 patients. Postpartum disease activity was recorded in 135 pregnancies.CONCLUSION:
Disease activity improved in 60% of patients with RA in pregnancy and flared in 46.7% postpartum.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Gravidez
Tipo de estudo:
Observational_studies
/
Systematic_reviews
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article