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Electrophysiological evaluation of pentamidine and 17-AAG in human stem cell-derived cardiomyocytes for safety assessment.
Asahi, Yumiko; Nomura, Fumimasa; Abe, Yasuyuki; Doi, Masafumi; Sakakura, Tomoko; Takasuna, Kiyoshi; Yasuda, Kenji.
Afiliação
  • Asahi Y; Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Edogawa, Tokyo 134-8630, Japan. Electronic address: okimoto.yumiko.bc@daiichisankyo.co.jp.
  • Nomura F; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo 101-0062, Japan.
  • Abe Y; Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Edogawa, Tokyo 134-8630, Japan.
  • Doi M; Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Edogawa, Tokyo 134-8630, Japan.
  • Sakakura T; Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Edogawa, Tokyo 134-8630, Japan.
  • Takasuna K; Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Edogawa, Tokyo 134-8630, Japan.
  • Yasuda K; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo 101-0062, Japan; Organization for University Research Initiatives, Waseda University, 3-14-9 Okubo, Shinjuku, Tokyo 169-0072, Japan; Waseda Bioscience Research Institute in Singa
Eur J Pharmacol ; 842: 221-230, 2019 Jan 05.
Article em En | MEDLINE | ID: mdl-30391349
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pentamidina / Segurança / Células-Tronco / Benzoquinonas / Miócitos Cardíacos / Lactamas Macrocíclicas / Fenômenos Eletrofisiológicos Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pentamidina / Segurança / Células-Tronco / Benzoquinonas / Miócitos Cardíacos / Lactamas Macrocíclicas / Fenômenos Eletrofisiológicos Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article