DNA Modified with Boronâ»Metal Cluster Complexes [M(C2B9H11)2]-Synthesis, Properties, and Applications.
Int J Mol Sci
; 19(11)2018 Nov 07.
Article
em En
| MEDLINE
| ID: mdl-30405023
ABSTRACT
Together with tremendous progress in biotechnology, nucleic acids, while retaining their status as "molecules of life", are becoming "molecular wires", materials for the construction of molecular structures at the junction between the biological and abiotic worlds. Herein, we present an overview of the approaches for incorporating metal centers into nucleic acids based on metalâ»boron cluster complexes (metallacarboranes) as the metal carriers. The methods are modular and versatile, allowing practical access to innovative metal-containing DNA for various applications, such as nucleic acid therapeutics, electrochemical biosensors, infrared-sensitive probes, and building blocks for nanoconstruction.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Boro
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DNA
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Complexos de Coordenação
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article