The therapeutic potential of the insect metalloproteinase inhibitor against infections caused by Pseudomonas aeruginosa.

Eisenhardt, Michaela; Schlupp, Peggy; Höfer, Frank; Schmidts, Thomas; Hoffmann, Daniel; Czermak, Peter; Pöppel, Anne-Kathrin; Vilcinskas, Andreas; Runkel, Frank

Eisenhardt, Michaela; Schlupp, Peggy; Höfer, Frank; Schmidts, Thomas; Hoffmann, Daniel; Czermak, Peter; Pöppel, Anne-Kathrin; Vilcinskas, Andreas; Runkel, Frank.

Afiliação

Eisenhardt M; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen, Giessen, Germany.
Schlupp P; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen, Giessen, Germany.
Höfer F; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen, Giessen, Germany.
Schmidts T; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen, Giessen, Germany.
Hoffmann D; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen, Giessen, Germany.
Czermak P; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen, Giessen, Germany.
Pöppel AK; Department of Bio-Resources, Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Giessen, Germany.
Vilcinskas A; Department of Bio-Resources, Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Giessen, Germany.
Runkel F; Department of Bio-Resources, Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Giessen, Germany.

J Pharm Pharmacol ; 71(3): 316-328, 2019 Mar.

Article em En | MEDLINE | ID: mdl-30408181

Assuntos

Proteínas de Insetos/farmacologia; Insetos/metabolismo; Inibidores de Metaloproteinases de Matriz/farmacologia; Infecções por Pseudomonas/tratamento farmacológico; Pseudomonas aeruginosa/efeitos dos fármacos; Proteínas Recombinantes de Fusão/farmacologia; Animais; Antibacterianos/farmacologia; Linhagem Celular; Movimento Celular/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Glutationa Transferase/farmacologia; Humanos; Queratinócitos/efeitos dos fármacos; Mariposas/metabolismo; Suínos; Termolisina/farmacologia

Palavras-chave

IMPI; LasB; Pseudolysin; Pseudomonas aeruginosa secretome; ex vivo porcine wound model

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Infecções por Pseudomonas / Proteínas Recombinantes de Fusão / Proteínas de Insetos / Inibidores de Metaloproteinases de Matriz / Insetos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google