The VICM biomarker is released from activated macrophages and inhibited by anti-GM-CSFR&#945;-mAb treatment in rheumatoid arthritis patients.

Mortensen, Joachim Høg; Guo, Xiang; De Los Reyes, Melissa; Dziegiel, Morten Hanefeld; Karsdal, Morten Asser; Bay-Jensen, Anne Christine; White, Wendy I

The VICM biomarker is released from activated macrophages and inhibited by anti-GM-CSFRα-mAb treatment in rheumatoid arthritis patients.

Mortensen, Joachim Høg; Guo, Xiang; De Los Reyes, Melissa; Dziegiel, Morten Hanefeld; Karsdal, Morten Asser; Bay-Jensen, Anne Christine; White, Wendy I.

Afiliação

Mortensen JH; Nordic Bioscience, Biomarkers and Research, Herlev, Denmark. jhm@nordicbio.com.
Guo X; MedImmune LLC, Gaithersburg, MD, USA.
De Los Reyes M; MedImmune LLC, Gaithersburg, MD, USA.
Dziegiel MH; Department of Clinical Immunology, Blood Bank, Rigshospitalet, Copenhagen University Hospital, Denmark.
Karsdal MA; Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Bay-Jensen AC; Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
White WI; MedImmune LLC, Gaithersburg, MD, USA.

Clin Exp Rheumatol ; 37(1): 73-80, 2019.

Article em En | MEDLINE | ID: mdl-30418117

Assuntos

Artrite Reumatoide; Macrófagos/metabolismo; Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos/antagonistas & inibidores; Anticorpos Monoclonais; Anticorpos Monoclonais Humanizados; Artrite Reumatoide/tratamento farmacológico; Artrite Reumatoide/imunologia; Artrite Reumatoide/metabolismo; Biomarcadores; Humanos; Leucócitos Mononucleares; Desiminases de Arginina em Proteínas; Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos/imunologia

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Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Macrófagos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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