Where Are We Going with Sentinel Lymph Node Mapping in Gynecologic Cancers?
Curr Oncol Rep
; 20(12): 96, 2018 11 13.
Article
em En
| MEDLINE
| ID: mdl-30421035
ABSTRACT
PURPOSE OF REVIEW Sentinel lymph node (SLN) mapping is a standard of care for lymphatic assessment of many early-stage gynecologic malignancies. We review the current data, emphasizing the utility of SLN mapping in the management of gynecologic cancers. RECENT FINDINGS:
Endometrial cancer recent studies have focused on confirming the safety and efficacy of SLN mapping for high-risk patients. Cervical cancer the LACC Trial demonstrated reduced survival with minimally invasive surgery, calling into question the validity of prior studies evaluating SLN mapping with a minimally invasive approach. Vulvar cancer the ongoing GROINS-V-II trial is investigating whether patients with SLN metastasis < 2 mm in diameter can safely undergo adjuvant radiation ± chemotherapy without completion inguinal lymphadenectomy. NCCN guidelines have incorporated SLN mapping as a lymphatic assessment strategy for endometrial, cervical, and vulvar malignancies. SLN mapping appears to reduce morbidity while still maintaining an appropriate detection rate of lymphatic metastasis. Additional clinical trials will further our knowledge of these procedures.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Biópsia de Linfonodo Sentinela
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Linfonodo Sentinela
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Neoplasias dos Genitais Femininos
Tipo de estudo:
Guideline
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Prognostic_studies
Limite:
Female
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Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article