High throughput screening reveals no significant changes in protein synthesis, processing, and degradation machinery during passaging of mesenchymal stem cells <sup>1</sup>.

Sequiera, Glen Lester; Sareen, Niketa; Sharma, Vikram; Surendran, Arun; Abu-El-Rub, Ejlal; Ravandi, Amir; Dhingra, Sanjiv

High throughput screening reveals no significant changes in protein synthesis, processing, and degradation machinery during passaging of mesenchymal stem cells ¹.

Sequiera, Glen Lester; Sareen, Niketa; Sharma, Vikram; Surendran, Arun; Abu-El-Rub, Ejlal; Ravandi, Amir; Dhingra, Sanjiv.

Afiliação

Sequiera GL; a Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre, Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R2H 2A6, Canada.
Sareen N; b Regenerative Medicine Program, University of Manitoba, Winnipeg, MB R3E 0W2, Canada.
Sharma V; a Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre, Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R2H 2A6, Canada.
Surendran A; b Regenerative Medicine Program, University of Manitoba, Winnipeg, MB R3E 0W2, Canada.
Abu-El-Rub E; c School of Biomedical and Healthcare Sciences, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, England.
Ravandi A; a Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre, Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R2H 2A6, Canada.
Dhingra S; a Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre, Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R2H 2A6, Canada.

Can J Physiol Pharmacol ; 97(6): 536-543, 2019 Jun.

Article em En | MEDLINE | ID: mdl-30422687

Assuntos

Células-Tronco Mesenquimais/citologia; Biossíntese de Proteínas; Proteômica; Animais; Técnicas de Cultura de Células; Diferenciação Celular; Retículo Endoplasmático/metabolismo; Masculino; Transplante de Células-Tronco Mesenquimais; Ratos; Ratos Sprague-Dawley; Ribossomos/metabolismo

Palavras-chave

analyse protéomique; cellules souches mésenchymateuses; greffe; mesenchymal stem cells; proteomic analysis; regenerative therapy; thérapie régénératrice; transplantation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Proteômica / Células-Tronco Mesenquimais Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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