The post hoc analysis comparing the severity grades of chemoradiotherapy-induced oral mucositis scored between the central and local assessors in a multicenter, randomized controlled trial of rebamipide for head and neck cancer.

Ueno, Takao; Zenda, Sadamoto; Konishi, Tetsuhito; Yurikusa, Takashi; Shibasaki, Yoshiyuki; Nagamoto, Hisashi; Fujii, Masato

Ueno, Takao; Zenda, Sadamoto; Konishi, Tetsuhito; Yurikusa, Takashi; Shibasaki, Yoshiyuki; Nagamoto, Hisashi; Fujii, Masato.

Afiliação

Ueno T; Department of General Internal Medicine, Dentistry, Oncologic Emergency, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Zenda S; Division of Radiation Oncology and Particle Therapy, National Cancer Center Hospital East, 6-5-1 Kashiwa-no-ha, Kashiwa, Chiba, 277-8577, Japan. szenda@east.ncc.go.jp.
Konishi T; Innovation Center for Supportive, Palliative and Psychosocial Care, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. szenda@east.ncc.go.jp.
Yurikusa T; Department of Dentistry, National Cancer Center Hospital East, 6-5-1 Kashiwa-no-ha, Kashiwa, Chiba, 277-8577, Japan.
Shibasaki Y; Division of Dentistry and Oral Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.
Nagamoto H; Medical Affairs, Otsuka Pharmaceutical Co., Ltd., Shinagawa Grad Central Tower 2-16-4, Konan, Minato-ku, Tokyo, 108-8242, Japan.
Fujii M; Medical Affairs, Otsuka Pharmaceutical Co., Ltd., 463-10 Kagasuno, Kawauchi-cho, Tokushima, 771-0192, Japan.

Int J Clin Oncol ; 24(3): 241-247, 2019 Mar.

Article em En | MEDLINE | ID: mdl-30426268

Assuntos

Alanina/análogos & derivados; Quimiorradioterapia/efeitos adversos; Neoplasias de Cabeça e Pescoço/tratamento farmacológico; Quinolonas/efeitos adversos; Estomatite/etiologia; Idoso; Alanina/efeitos adversos; Método Duplo-Cego; Feminino; Neoplasias de Cabeça e Pescoço/radioterapia; Humanos; Masculino; Pessoa de Meia-Idade; Placebos; Estomatite/induzido quimicamente

Palavras-chave

Chemoradiotherapy-induced oral mucositis; Common Terminology Criteria for Adverse Events (CTCAE) version 3.0; Head and neck cancer; Independent central review; Post hoc analysis; Rebamipide liquid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estomatite / Quinolonas / Alanina / Quimiorradioterapia / Neoplasias de Cabeça e Pescoço Tipo de estudo: Clinical_trials Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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