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Inhibition of mRNA processing activity from ginger-, clove- and cinnamon-extract, and by two ginger constituents, 6-gingerol and 6-shogaol.
Morimoto, Mari; Mitsukawa, Mizuki; Fujiwara, Chisato; Kawamura, Yukio; Masuda, Seiji.
Afiliação
  • Morimoto M; a Division of Integrated Life Sciences, Graduate School of Biostudies , Kyoto University , Kyoto , Japan.
  • Mitsukawa M; b Department of Food and Nutrition , Kyoto Women's University , Kyoto , Japan.
  • Fujiwara C; a Division of Integrated Life Sciences, Graduate School of Biostudies , Kyoto University , Kyoto , Japan.
  • Kawamura Y; b Department of Food and Nutrition , Kyoto Women's University , Kyoto , Japan.
  • Masuda S; b Department of Food and Nutrition , Kyoto Women's University , Kyoto , Japan.
Biosci Biotechnol Biochem ; 83(3): 498-501, 2019 Mar.
Article em En | MEDLINE | ID: mdl-30426858
ABSTRACT
Inhibition of mRNA processing, including splicing in the nucleus, is a potential anti-cancer candidate. To obtain mRNA processing inhibitors, we have screened for active constituents from spices. Ginger, clove, and cinnamon showed an inhibitory effect on mRNA processing in the nucleus. Two components in ginger, 6-gingerol and 6-shogaol, exhibited the inhibition of mRNA processing.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Catecóis / Cinnamomum zeylanicum / Zingiber officinale / Syzygium / Álcoois Graxos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Catecóis / Cinnamomum zeylanicum / Zingiber officinale / Syzygium / Álcoois Graxos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article