Long Noncoding RNA HOST2 Promotes Epithelial-Mesenchymal Transition, Proliferation, Invasion and Migration of Hepatocellular Carcinoma Cells by Activating the JAK2-STAT3 Signaling Pathway.

Wu, Yang; Yuan, Tan; Wang, Wei-Wei; Ge, Peng-Lei; Gao, Zhi-Qiang; Zhang, Gong; Tang, Zhe; Dang, Xiao-Wei; Zhao, Yong-Fu; Zhang, Jian-Ying; Jiang, Guo-Zhong

Wu, Yang; Yuan, Tan; Wang, Wei-Wei; Ge, Peng-Lei; Gao, Zhi-Qiang; Zhang, Gong; Tang, Zhe; Dang, Xiao-Wei; Zhao, Yong-Fu; Zhang, Jian-Ying; Jiang, Guo-Zhong.

Afiliação

Wu Y; Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Chinasunnywu@zzu.edu.cn.
Yuan T; Department of Respiratory, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wang WW; Department of Pathology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ge PL; Department of Pathology, School of Basic Medicine, Zhengzhou University, Zhengzhou, China.
Gao ZQ; Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang G; Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Tang Z; Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Dang XW; Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhao YF; Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang JY; Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jiang GZ; Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China.

Cell Physiol Biochem ; 51(1): 301-314, 2018.

Article em En | MEDLINE | ID: mdl-30453302

Assuntos

Proliferação de Células; Transição Epitelial-Mesenquimal; Janus Quinase 2/metabolismo; RNA Longo não Codificante/metabolismo; Fator de Transcrição STAT3/metabolismo; Adulto; Idoso; Caderinas/genética; Caderinas/metabolismo; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; Movimento Celular; Feminino; Humanos; Janus Quinase 2/genética; Neoplasias Hepáticas/patologia; Masculino; Pessoa de Meia-Idade; Interferência de RNA; RNA Longo não Codificante/antagonistas & inibidores; RNA Longo não Codificante/genética; RNA Interferente Pequeno/metabolismo; Fator de Transcrição STAT3/genética; Transdução de Sinais; Vimentina/genética; Vimentina/metabolismo

Palavras-chave

Epithelial-mesenchymal transition; Hepatocellular carcinoma cells; Invasion; JAK2-STAT3 signaling pathway; Long noncoding RNA HOST2; Migration; Proliferation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proliferação de Células / Fator de Transcrição STAT3 / Janus Quinase 2 / Transição Epitelial-Mesenquimal / RNA Longo não Codificante Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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