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Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.
Chen, Bo; Vousden, Katherine A; Naiman, Brian; Turman, Sean; Sun, Hong; Wang, Shu; Vinall, Lisa M K; Kemp, Benjamin P; Kasturiangan, Srinath; Rees, D Gareth; Grant, Ethan; Hinrichs, Mary Jane; Eck, Steven; DiGiandomenico, Antonio; Jack Borrok, M; Ly, Neang; Xiong, Ximing; Gonzalez, Carlos; Morehouse, Christopher; Wang, Yue; Zhou, Yebin; Cann, Jennifer; Zhao, Weiguang; Koelkebeck, Holly; Okubo, Koshu; Mayadas, Tanya N; Howe, David; Griffiths, Janet; Kolbeck, Roland; Herbst, Ronald; Sims, Gary P.
Afiliação
  • Chen B; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA Chenb@medimmune.com SimsG@MedImmune.com.
  • Vousden KA; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK.
  • Naiman B; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Turman S; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Sun H; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Wang S; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Vinall LMK; Viela Bio, Gaithersburg, Maryland, USA.
  • Kemp BP; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK.
  • Kasturiangan S; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK.
  • Rees DG; Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Grant E; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK.
  • Hinrichs MJ; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Eck S; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • DiGiandomenico A; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Jack Borrok M; Microbial Sciences, MedImmune, LLC, Gaithersburg, Maryland, USA.
  • Ly N; Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Xiong X; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Gonzalez C; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Morehouse C; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Wang Y; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Zhou Y; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Cann J; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Zhao W; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Koelkebeck H; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Okubo K; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Mayadas TN; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Howe D; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Griffiths J; Department of Clinical Development, MedImmune Ltd, Granta Park, Great Abington, UK.
  • Kolbeck R; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Herbst R; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
  • Sims GP; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
Ann Rheum Dis ; 78(2): 228-237, 2019 02.
Article em En | MEDLINE | ID: mdl-30459279
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Anticorpos Anti-Idiotípicos / Receptores de IgG / Fatores Imunológicos / Complexo Antígeno-Anticorpo Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Anticorpos Anti-Idiotípicos / Receptores de IgG / Fatores Imunológicos / Complexo Antígeno-Anticorpo Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article