Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNF-&#945;-induced VCAM-1 expression and monocytic cell adhesion.

Fan, Xing; Chen, Xiaolin; Feng, Qi; Peng, Kai; Wu, Qianqian; Passerini, Anthony G; Simon, Scott I; Sun, ChongXiu

Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNF-α-induced VCAM-1 expression and monocytic cell adhesion.

Fan, Xing; Chen, Xiaolin; Feng, Qi; Peng, Kai; Wu, Qianqian; Passerini, Anthony G; Simon, Scott I; Sun, ChongXiu.

Afiliação

Fan X; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University , Nanjing , China.
Chen X; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University , Nanjing , China.
Feng Q; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University , Nanjing , China.
Peng K; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University , Nanjing , China.
Wu Q; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University , Nanjing , China.
Passerini AG; Department of Biomedical Engineering, University of California , Davis, California.
Simon SI; Department of Biomedical Engineering, University of California , Davis, California.
Sun C; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University , Nanjing , China.

Am J Physiol Heart Circ Physiol ; 316(2): H408-H420, 2019 02 01.

Article em En | MEDLINE | ID: mdl-30462552

Assuntos

Aterosclerose/metabolismo; Adesão Celular; Células Endoteliais/metabolismo; Fator de Transcrição GATA6/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Molécula 1 de Adesão de Célula Vascular/metabolismo; Aorta/citologia; Aorta/metabolismo; Células Cultivadas; Regulação para Baixo; Células Endoteliais/efeitos dos fármacos; Células Endoteliais/fisiologia; Endotélio Vascular/citologia; Endotélio Vascular/metabolismo; Fator de Transcrição GATA6/genética; Humanos; Monócitos/fisiologia; Proteína Quinase C-alfa/metabolismo; Transdução de Sinais; Serina-Treonina Quinases TOR/genética; Fator de Necrose Tumoral alfa/farmacologia; Molécula 1 de Adesão de Célula Vascular/genética

Palavras-chave

GATA6; atherosclerosis; endothelium; vascular cell adhesion molecule 1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adesão Celular / Molécula 1 de Adesão de Célula Vascular / Células Endoteliais / Aterosclerose / Fator de Transcrição GATA6 / Serina-Treonina Quinases TOR Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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