Cell Membrane Coated Nanoparticles: An Emerging Biomimetic Nanoplatform for Targeted Bioimaging and Therapy.
Adv Exp Med Biol
; 1064: 45-59, 2018.
Article
em En
| MEDLINE
| ID: mdl-30471025
ABSTRACT
Biomimetic nanoplatform being a recent and emerging strategy plays an important role in a wide variety of applications. The different types of membranes used for coating include membranes from red blood cells, platelets, leucocytes, neutrophils, cancer cells, stem cells, etc. The as obtained membrane vesicles are fused onto the core nanoparticles through extrusion, sonication, electroporation. Biomimetic nanoparticles attain special functions which include ligand recognition and targeting, long blood circulation, immune escaping, tumor targeting depending on the core-shell interactions. The membrane coated nanoparticles indeed mimic the source cells and improves the therapeutic efficacy of drugs other cargos through specific delivery and enhanced accumulation in the tumor.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Membrana Celular
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Sistemas de Liberação de Medicamentos
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Materiais Biomiméticos
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Nanopartículas
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article