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CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
Suárez-Calvet, Marc; Capell, Anja; Araque Caballero, Miguel Ángel; Morenas-Rodríguez, Estrella; Fellerer, Katrin; Franzmeier, Nicolai; Kleinberger, Gernot; Eren, Erden; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M; Cruchaga, Carlos; Paumier, Katrina; Bateman, Randall J; Fagan, Anne M; Morris, John C; Levin, Johannes; Danek, Adrian; Jucker, Mathias; Masters, Colin L; Rossor, Martin N; Ringman, John M; Shaw, Leslie M; Trojanowski, John Q; Weiner, Michael; Ewers, Michael; Haass, Christian.
Afiliação
  • Suárez-Calvet M; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany msuarez@barcelonabeta.org christian.haass@mail03.med.uni-muenchen.de.
  • Capell A; German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany.
  • Araque Caballero MÁ; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Morenas-Rodríguez E; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Fellerer K; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Franzmeier N; Department of Neurology, Institut d'Investigacions Biomèdiques, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.
  • Kleinberger G; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Eren E; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Deming Y; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Piccio L; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Karch CM; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Cruchaga C; Izmir International Biomedicine and Genome Institute Dokuz, Eylul University, Izmir, Turkey.
  • Paumier K; Department of Neuroscience, Institute of Health Sciences, Dokuz Eylul University, Izmir, Turkey.
  • Bateman RJ; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
  • Fagan AM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
  • Morris JC; Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA.
  • Levin J; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
  • Danek A; Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA.
  • Jucker M; Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Masters CL; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
  • Rossor MN; Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA.
  • Ringman JM; Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Shaw LM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
  • Trojanowski JQ; Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA.
  • Weiner M; Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA.
  • Ewers M; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
  • Haass C; Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA.
EMBO Mol Med ; 10(12)2018 12.
Article em En | MEDLINE | ID: mdl-30482868
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Doença de Alzheimer / Disfunção Cognitiva / Progranulinas Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Doença de Alzheimer / Disfunção Cognitiva / Progranulinas Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article