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B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward immune evasion?
Yamano, Tomoyoshi; Steinert, Madlen; Steer, Beatrix; Klein, Ludger; Hammerschmidt, Wolfgang; Adler, Heiko.
Afiliação
  • Yamano T; Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Steinert M; Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Steer B; Research Unit Lung Repair and Regeneration, Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Munich, Germany.
  • Klein L; University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany.
  • Hammerschmidt W; Member of the German Center of Lung Research (DZL), Munich, Germany.
  • Adler H; Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany.
Eur J Immunol ; 49(2): 351-352, 2019 02.
Article em En | MEDLINE | ID: mdl-30488950
ABSTRACT
We show that latently gammaherpesvirus-infected B cells are present in the thymus. This could result in a functional T-cell tolerance against certain viral epitopes. It is conceivable that also antigens from other viruses or pathogens may be conveyed to the thymus for their immune evasion.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timo / Linfócitos B / Rhadinovirus / Infecções por Herpesviridae / Evasão da Resposta Imune / Tolerância Imunológica Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timo / Linfócitos B / Rhadinovirus / Infecções por Herpesviridae / Evasão da Resposta Imune / Tolerância Imunológica Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article