Molecular evidence and risk factors of Coxiella burnetii among seropositive high-risk individuals in the center of Iran.
Comp Immunol Microbiol Infect Dis
; 61: 34-37, 2018 Dec.
Article
em En
| MEDLINE
| ID: mdl-30502831
ABSTRACT
This study evaluated the prevalence of C. burnetii DNA in blood samples of the high-risk population in central Iran. In spring 2015, a nested PCR was applied to detect C. burnetii DNA in 173 blood samples from seropositive high-risk individuals in Isfahan County. A checklist was used for extracting data. Univariate tests and multivariable binary logistic regression were performed to analyze the data and P values < 0.05 were considered significant. In total, 9.83% of the samples were positive and an association was found between the prevalence of C. burnetii DNA and the presence of IgG antibodies against phase I and/or II (P = 0.04) in univariate analysis. However, in multivariable logistic regression model, no risk factor was seen. This study revealed that high-risk populations in Isfahan County had been exposed to C. burnetii. This can alert health policymakers to the possibility of a Q fever epidemic in the region.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Febre Q
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Imunoglobulina G
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Coxiella burnetii
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Anticorpos Antibacterianos
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Animals
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Female
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Humans
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Male
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article