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The combination of metformin and 2-deoxyglucose significantly inhibits cyst formation in miniature pigs with polycystic kidney disease.
Lian, Xiaoying; Wu, Xiaoyuan; Li, Zhongxin; Zhang, Yingjie; Song, Kangkang; Cai, Guangyan; Li, Qinggang; Lin, Shupeng; Chen, Xiangmei; Bai, Xue-Yuan.
Afiliação
  • Lian X; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
  • Wu X; Department of Nephrology, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
  • Li Z; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
  • Zhang Y; Department of Nephrology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Song K; Department of Nephrology, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
  • Cai G; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
  • Li Q; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
  • Lin S; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
  • Chen X; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
  • Bai XY; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
Br J Pharmacol ; 176(5): 711-724, 2019 03.
Article em En | MEDLINE | ID: mdl-30515768

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rim Policístico Autossômico Dominante / Desoxiglucose / Metformina Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rim Policístico Autossômico Dominante / Desoxiglucose / Metformina Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article