Yeast-like filamentous fungi: Molecular identification and in vitro susceptibility study.
Med Mycol
; 57(7): 909-913, 2019 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-30521007
ABSTRACT
Yeast-like filamentous fungi, collected in Italy from 1985 to 2018, were submitted to molecular identification and antifungal susceptibility testings. Clinical isolates were identified as Magnusiomyces capitatus (28), M. clavatus (18), and Geotrichum candidum (2). M. clavatus was prevalent among blood isolates (18/24), M. capitatus among isolates from other biological materials. The intrinsic echinocandin resistance was confirmed. Both species had low minimum inhibitory concentrations (MICs) of itraconazole, posaconazole, and voriconazole, while M. clavatus had lower MIC of flucytosine and higher MIC of isavuconazole than M. capitatus. The intrinsic resistance of these species to echinocandins could be the reason of the recent increase of M. clavatus bloodstream infections.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fungos
/
Antifúngicos
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article