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Universal screening for Lynch syndrome in a large consecutive cohort of Chinese colorectal cancer patients: High prevalence and unique molecular features.
Jiang, Wu; Cai, Mu-Yan; Li, Shi-Yong; Bei, Jin-Xin; Wang, Fang; Hampel, Heather; Ling, Yi-Hong; Frayling, Ian M; Sinicrope, Frank A; Rodriguez-Bigas, Miguel A; Dignam, James J; Kerr, David J; Rosell, Rafael; Mao, Mao; Li, Ji-Bin; Guo, Yun-Miao; Wu, Xiao-Yan; Kong, Ling-Heng; Tang, Jing-Hua; Wu, Xiao-Dan; Li, Chao-Feng; Chen, Jie-Rong; Ou, Qing-Jian; Ye, Ming-Zhi; Guo, Feng-Ming; Han, Peng; Wang, Qi-Wei; Wan, De-Sen; Li, Li; Xu, Rui-Hua; Pan, Zhi-Zhong; Ding, Pei-Rong.
Afiliação
  • Jiang W; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Cai MY; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Li SY; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Bei JX; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Wang F; BGI-Guangzhou Medical Laboratory, BGI-Shenzhen, People's Republic of China.
  • Hampel H; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Ling YH; Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Frayling IM; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Sinicrope FA; Department of Molecular Diagnostics, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Rodriguez-Bigas MA; Division of Human Genetics, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
  • Dignam JJ; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Kerr DJ; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Rosell R; Institute of Cancer and Genetics, Cardiff University, Cardiff, United Kingdom.
  • Mao M; All-Wales Medical Genetics Service, Institute of Medical Genetics, University Hospital of Wales, Cardiff, United Kingdom.
  • Li JB; Department of Oncology, Mayo Clinic, Rochester, MN.
  • Guo YM; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Wu XY; Department of Public Health Sciences, The University of Chicago Biological Sciences, Chicago, IL.
  • Kong LH; Department of Clinical Pharmacology, OCRB, Churchill Campus, Headington, University of Oxford, Oxford, United Kingdom.
  • Tang JH; Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Barcelona, Spain.
  • Wu XD; BGI-Guangzhou Medical Laboratory, BGI-Shenzhen, People's Republic of China.
  • Li CF; Department of Clinical Research, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Chen JR; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Ou QJ; Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Ye MZ; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Guo FM; Department of Molecular Diagnostics, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Han P; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Wang QW; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Wan DS; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Li L; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Xu RH; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
  • Pan ZZ; Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
  • Ding PR; Department of Information Technology, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
Int J Cancer ; 144(9): 2161-2168, 2019 05 01.
Article em En | MEDLINE | ID: mdl-30521064

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Programas de Rastreamento / Proteínas Proto-Oncogênicas B-raf / Reparo de Erro de Pareamento de DNA / Proteína 1 Homóloga a MutL Tipo de estudo: Diagnostic_studies / Guideline / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Programas de Rastreamento / Proteínas Proto-Oncogênicas B-raf / Reparo de Erro de Pareamento de DNA / Proteína 1 Homóloga a MutL Tipo de estudo: Diagnostic_studies / Guideline / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article