Trained murine mesenchymal stem cells have anti-inflammatory effect on macrophages, but defective regulation on T-cell proliferation.

Lin, Tzuhua; Pajarinen, Jukka; Kohno, Yusuke; Huang, Jhih-Fong; Maruyama, Masahiro; Romero-Lopez, Monica; Nathan, Karthik; Yao, Zhenyu; Goodman, Stuart B

Lin, Tzuhua; Pajarinen, Jukka; Kohno, Yusuke; Huang, Jhih-Fong; Maruyama, Masahiro; Romero-Lopez, Monica; Nathan, Karthik; Yao, Zhenyu; Goodman, Stuart B.

Afiliação

Lin T; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Pajarinen J; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Kohno Y; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Huang JF; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Maruyama M; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Romero-Lopez M; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Nathan K; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Yao Z; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.
Goodman SB; Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California, USA; and.

FASEB J ; 33(3): 4203-4211, 2019 03.

Article em En | MEDLINE | ID: mdl-30521384

Assuntos

Proliferação de Células/fisiologia; Inflamação/imunologia; Macrófagos/imunologia; Células-Tronco Mesenquimais/imunologia; Linfócitos T/imunologia; Animais; Biomarcadores/metabolismo; Células Cultivadas; Técnicas de Cocultura/métodos; Citocinas/imunologia; Imunomodulação/imunologia; Inflamação/metabolismo; Ativação Linfocitária/imunologia; Macrófagos/metabolismo; Masculino; Células-Tronco Mesenquimais/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Transdução de Sinais/imunologia; Linfócitos T/metabolismo

Palavras-chave

T lymphocyte; immunomodulation; trained immunity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Proliferação de Células / Células-Tronco Mesenquimais / Inflamação / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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