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SKF-10047, a prototype Sigma-1 receptor agonist, augmented the membrane trafficking and uptake activity of the serotonin transporter and its C-terminus-deleted mutant via a Sigma-1 receptor-independent mechanism.
Asano, Masaya; Motoike, Serika; Yokota, Chika; Usuki, Naoto; Yamamoto, Hikaru; Urabe, Tomoaki; Katarao, Kazusa; Hide, Izumi; Tanaka, Shigeru; Kawamoto, Masashi; Irifune, Masahiro; Sakai, Norio.
Afiliação
  • Asano M; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Motoike S; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan; Department of Dental Anesthesiology, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2
  • Yokota C; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Usuki N; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Yamamoto H; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Urabe T; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan; Department of Anesthesiology and Critical Care, Graduate School of Biomedical & Health Sciences, Hiroshima Univ
  • Katarao K; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Hide I; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Tanaka S; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Kawamoto M; Department of Anesthesiology and Critical Care, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Irifune M; Department of Dental Anesthesiology, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan.
  • Sakai N; Department of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kausmi, Minami-ku, Hiroshima 734-8551, Japan. Electronic address: nsakai@hiroshima-u.ac.jp.
J Pharmacol Sci ; 139(1): 29-36, 2019 Jan.
Article em En | MEDLINE | ID: mdl-30522963
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenazocina / Membrana Celular / Receptores sigma / Proteínas da Membrana Plasmática de Transporte de Serotonina Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenazocina / Membrana Celular / Receptores sigma / Proteínas da Membrana Plasmática de Transporte de Serotonina Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article