Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke.

Kurisu, Kota; Zheng, Zhen; Kim, Jong Youl; Shi, Jian; Kanoke, Atsushi; Liu, Jialing; Hsieh, Christine L; Yenari, Midori A

Kurisu, Kota; Zheng, Zhen; Kim, Jong Youl; Shi, Jian; Kanoke, Atsushi; Liu, Jialing; Hsieh, Christine L; Yenari, Midori A.

Afiliação

Kurisu K; Department of Neurology, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Zheng Z; Department of Neurology, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Kim JY; Department of Neurology, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Shi J; Department of Neurology, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Kanoke A; Department of Neurosurgery, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Liu J; Department of Neurosurgery, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Hsieh CL; Department of Medicine, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Yenari MA; Department of Neurology, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.

J Cereb Blood Flow Metab ; 39(10): 1906-1918, 2019 10.

Article em En | MEDLINE | ID: mdl-30523715

Assuntos

Encéfalo/imunologia; Glicoproteínas de Membrana/imunologia; Fagocitose; Receptores Imunológicos/imunologia; Acidente Vascular Cerebral/imunologia; Animais; Encéfalo/patologia; Masculino; Glicoproteínas de Membrana/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Microglia/imunologia; Microglia/patologia; Células Mieloides/imunologia; Células Mieloides/patologia; Fagócitos/imunologia; Fagócitos/patologia; Receptores Imunológicos/genética; Acidente Vascular Cerebral/genética; Acidente Vascular Cerebral/patologia

Palavras-chave

Bone marrow; microglia; phagocytosis; stroke; triggering receptor expressed on myeloid cells-2

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fagocitose / Encéfalo / Glicoproteínas de Membrana / Receptores Imunológicos / Acidente Vascular Cerebral Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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