Polymorphisms of NAT2, CYP2E1, GST, and HLA related to drug-induced liver injury in indonesian tuberculosis patients.

Perwitasari, Dyah Aryani; Darmawan, Endang; Mulyani, Ully Adhi; Vlies, Pieter Van Der; Alffenaar, Jan-Willem C; Atthobar, Jarir; Wilffert, Bob

Perwitasari, Dyah Aryani; Darmawan, Endang; Mulyani, Ully Adhi; Vlies, Pieter Van Der; Alffenaar, Jan-Willem C; Atthobar, Jarir; Wilffert, Bob.

Afiliação

Perwitasari DA; Unit of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Indonesia.
Darmawan E; Unit of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Indonesia.
Mulyani UA; Center of Health Technology and Clinical Epidemiology, National Health Institute, Jakarta, Indonesia.
Vlies PV; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Alffenaar JC; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Atthobar J; Unit of Pharmacology and Therapy, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Wilffert B; Unit of PharmacoTherapy, Epidemiology and Economics, University of Groningen, Groningen Research Institute of Pharmacy, Groningen, The Netherlands.

Int J Mycobacteriol ; 7(4): 380-386, 2018.

Article em En | MEDLINE | ID: mdl-30531039

Assuntos

Antituberculosos/uso terapêutico; Arilamina N-Acetiltransferase/genética; Doença Hepática Induzida por Substâncias e Drogas/genética; Citocromo P-450 CYP2E1/genética; Glutationa Transferase/genética; Antígenos HLA/genética; Tuberculose/tratamento farmacológico; Adulto; Antituberculosos/sangue; Estudos de Casos e Controles; Feminino; Genótipo; Humanos; Indonésia/epidemiologia; Isoniazida/sangue; Isoniazida/uso terapêutico; Masculino; Pessoa de Meia-Idade; Razão de Chances; Fenótipo; Polimorfismo de Nucleotídeo Único; Estudos Prospectivos; Tuberculose/epidemiologia

Palavras-chave

Antituberculosis; CYP2E1; GST; HLA; Indonesia; NAT2; drug-induced liver injury

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arilamina N-Acetiltransferase / Tuberculose / Citocromo P-450 CYP2E1 / Doença Hepática Induzida por Substâncias e Drogas / Glutationa Transferase / Antígenos HLA / Antituberculosos Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País como assunto: Asia Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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