Prevention of mercaptopurine-induced hypoglycemia using allopurinol to reduce methylated thiopurine metabolites.

Miller, Matthew B; Brackett, Julienne; Schafer, Eric S; Rau, Rachel E

Miller, Matthew B; Brackett, Julienne; Schafer, Eric S; Rau, Rachel E.

Afiliação

Miller MB; Section of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Brackett J; Section of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Schafer ES; Section of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Rau RE; Section of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

Pediatr Blood Cancer ; 66(4): e27577, 2019 04.

Article em En | MEDLINE | ID: mdl-30548777

Assuntos

Hipoglicemia; Mercaptopurina; Tioguanina/metabolismo; Alopurinol/administração & dosagem; Alopurinol/farmacocinética; Criança; Feminino; Humanos; Hipoglicemia/sangue; Hipoglicemia/induzido quimicamente; Hipoglicemia/prevenção & controle; Masculino; Mercaptopurina/administração & dosagem; Mercaptopurina/efeitos adversos; Mercaptopurina/farmacocinética

Palavras-chave

6-mercaptopurine; acute lymphoblastic leukemia; allopurinol; hypoglycemia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tioguanina / Hipoglicemia / Mercaptopurina Limite: Child / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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