In vitro activity of EDTA and TOL-463 against Neisseria gonorrhoeae.
Diagn Microbiol Infect Dis
; 93(4): 369-371, 2019 Apr.
Article
em En
| MEDLINE
| ID: mdl-30552033
ABSTRACT
Neisseria gonorrhoeae quickly develops drug resistance. Time-kill curves revealed that EDTA and TOL-463 inhibit growth similar to penicillin, ciprofloxacin, and azithromycin. Furthermore, synergistic and additive antimicrobial interactions occurred when EDTA and TOL-463 were combined with penicillin or azithromycin, respectively, suggesting that further investigations into these unconventional antimicrobials may be advantageous.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácidos Bóricos
/
Ácido Edético
/
Antibacterianos
/
Neisseria gonorrhoeae
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article