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Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity.
Rached, Marie-Therese; Millership, Steven J; Pedroni, Silvia M A; Choudhury, Agharul I; Costa, Ana S H; Hardy, Darran G; Glegola, Justyna A; Irvine, Elaine E; Selman, Colin; Woodberry, Megan C; Yadav, Vijay K; Khadayate, Sanjay; Vidal-Puig, Antonio; Virtue, Samuel; Frezza, Christian; Withers, Dominic J.
Afiliação
  • Rached MT; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
  • Millership SJ; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
  • Pedroni SMA; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
  • Choudhury AI; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK.
  • Costa ASH; MRC Cancer Unit, University of Cambridge, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.
  • Hardy DG; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK.
  • Glegola JA; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK.
  • Irvine EE; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK.
  • Selman C; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.
  • Woodberry MC; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK.
  • Yadav VK; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK; Department of Genetics and Development, Columbia University, New York, 10032, USA.
  • Khadayate S; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK.
  • Vidal-Puig A; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, CB2 0QQ, UK.
  • Virtue S; University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, CB2 0QQ, UK.
  • Frezza C; MRC Cancer Unit, University of Cambridge, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.
  • Withers DJ; MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 0NN, UK. Electronic address: d.withers@imperial.ac.uk.
Mol Metab ; 20: 38-50, 2019 02.
Article em En | MEDLINE | ID: mdl-30553769
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Nervoso Simpático / Tecido Adiposo Marrom / Células Precursoras de Monócitos e Macrófagos / Proteínas Substratos do Receptor de Insulina / Obesidade Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Nervoso Simpático / Tecido Adiposo Marrom / Células Precursoras de Monócitos e Macrófagos / Proteínas Substratos do Receptor de Insulina / Obesidade Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article