Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis.

Ponath, Gerald; Lincoln, Matthew R; Levine-Ritterman, Maya; Park, Calvin; Dahlawi, Somiah; Mubarak, Mayyan; Sumida, Tomokazu; Airas, Laura; Zhang, Shun; Isitan, Cigdem; Nguyen, Thanh D; Raine, Cedric S; Hafler, David A; Pitt, David

Ponath, Gerald; Lincoln, Matthew R; Levine-Ritterman, Maya; Park, Calvin; Dahlawi, Somiah; Mubarak, Mayyan; Sumida, Tomokazu; Airas, Laura; Zhang, Shun; Isitan, Cigdem; Nguyen, Thanh D; Raine, Cedric S; Hafler, David A; Pitt, David.

Afiliação

Ponath G; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.
Lincoln MR; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.
Levine-Ritterman M; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06511, USA.
Park C; Broad Institute of MIT and Harvard University, Cambridge, MA, 02141, USA.
Dahlawi S; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.
Mubarak M; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.
Sumida T; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.
Airas L; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.
Zhang S; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.
Isitan C; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06511, USA.
Nguyen TD; Broad Institute of MIT and Harvard University, Cambridge, MA, 02141, USA.
Raine CS; Division of Clinical Neurosciences, University of Turku, Turku, 20520, Finland.
Hafler DA; Department of Radiology, Weill Cornell Medical College, New York, NY, 10021, USA.
Pitt D; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.

Nat Commun ; 9(1): 5337, 2018 12 17.

Article em En | MEDLINE | ID: mdl-30559390

Assuntos

Astrócitos/metabolismo; Sistema Nervoso Central/citologia; Esclerose Múltipla/genética; Subunidade p50 de NF-kappa B/genética; Células Cultivadas; Sistema Nervoso Central/patologia; Predisposição Genética para Doença/genética; Humanos; Esclerose Múltipla/patologia; Subunidade p50 de NF-kappa B/metabolismo; Polimorfismo de Nucleotídeo Único/genética; Fatores de Risco; Fator de Transcrição RelA/genética; Fator de Transcrição RelA/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Astrócitos / Subunidade p50 de NF-kappa B / Esclerose Múltipla Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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