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Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.
Menolfi, Demis; Jiang, Wenxia; Lee, Brian J; Moiseeva, Tatiana; Shao, Zhengping; Estes, Verna; Frattini, Mark G; Bakkenist, Christopher J; Zha, Shan.
Afiliação
  • Menolfi D; Institute for Cancer Genetics, Department of Pathology and Cell Biology, College of Physicians & Surgeons, Columbia University, New York, NY, 10032-3802, USA.
  • Jiang W; Institute for Cancer Genetics, Department of Pathology and Cell Biology, College of Physicians & Surgeons, Columbia University, New York, NY, 10032-3802, USA.
  • Lee BJ; Institute for Cancer Genetics, Department of Pathology and Cell Biology, College of Physicians & Surgeons, Columbia University, New York, NY, 10032-3802, USA.
  • Moiseeva T; Department of Radiation Oncology, University of Pittsburgh School of Medicine, Hillman Cancer Center, Research Pavilion, Suite 2.6, 5117 Centre Avenue, Pittsburgh, PA, 15213-1863, USA.
  • Shao Z; Institute for Cancer Genetics, Department of Pathology and Cell Biology, College of Physicians & Surgeons, Columbia University, New York, NY, 10032-3802, USA.
  • Estes V; Institute for Cancer Genetics, Department of Pathology and Cell Biology, College of Physicians & Surgeons, Columbia University, New York, NY, 10032-3802, USA.
  • Frattini MG; Department of Medicine, College of Physicians & Surgeons, Columbia University, New York, NY, 10032-3802, USA.
  • Bakkenist CJ; Department of Radiation Oncology, University of Pittsburgh School of Medicine, Hillman Cancer Center, Research Pavilion, Suite 2.6, 5117 Centre Avenue, Pittsburgh, PA, 15213-1863, USA.
  • Zha S; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Hillman Cancer Center, Research Pavilion, Suite 2.6, 5117 Centre Avenue, Pittsburgh, PA, 15213-1863, USA.
Nat Commun ; 9(1): 5351, 2018 12 17.
Article em En | MEDLINE | ID: mdl-30559436
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA de Cadeia Simples / Reparo do DNA Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA de Cadeia Simples / Reparo do DNA Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article