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Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.
Normand, Sylvain; Waldschmitt, Nadine; Neerincx, Andreas; Martinez-Torres, Ruben Julio; Chauvin, Camille; Couturier-Maillard, Aurélie; Boulard, Olivier; Cobret, Laetitia; Awad, Fawaz; Huot, Ludovic; Ribeiro-Ribeiro, Andre; Lautz, Katja; Ruez, Richard; Delacre, Myriam; Bondu, Clovis; Guilliams, Martin; Scott, Charlotte; Segal, Anthony; Amselem, Serge; Hot, David; Karabina, Sonia; Bohn, Erwin; Ryffel, Bernhard; Poulin, Lionel F; Kufer, Thomas A; Chamaillard, Mathias.
Afiliação
  • Normand S; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Waldschmitt N; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Neerincx A; Technische Universität München, Chair of Nutrition and Immunology, 85350, Freising-Weihenstephan, Germany.
  • Martinez-Torres RJ; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.
  • Chauvin C; Division of Medicine, University College London, WC1E 6BT, London, UK.
  • Couturier-Maillard A; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Boulard O; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Cobret L; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Awad F; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 933, F-75012, Paris, France.
  • Huot L; Inserm, UMR_S 933, F-75012, Paris, France.
  • Ribeiro-Ribeiro A; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 933, F-75012, Paris, France.
  • Lautz K; Inserm, UMR_S 933, F-75012, Paris, France.
  • Ruez R; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Delacre M; Division of Medicine, University College London, WC1E 6BT, London, UK.
  • Bondu C; Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
  • Guilliams M; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Scott C; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Segal A; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
  • Amselem S; Laboratory of Immunoregulation, VIB Inflammation Research Center, 9052, Ghent, Belgium.
  • Hot D; Department of Internal Medicine, Ghent University, Ghent, 9000, Belgium.
  • Karabina S; Laboratory of Immunoregulation, VIB Inflammation Research Center, 9052, Ghent, Belgium.
  • Bohn E; Department of Internal Medicine, Ghent University, Ghent, 9000, Belgium.
  • Ryffel B; Division of Medicine, University College London, WC1E 6BT, London, UK.
  • Poulin LF; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 933, F-75012, Paris, France.
  • Kufer TA; Inserm, UMR_S 933, F-75012, Paris, France.
  • Chamaillard M; University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.
Nat Commun ; 9(1): 5338, 2018 12 17.
Article em En | MEDLINE | ID: mdl-30559449
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilmuramil-Alanil-Isoglutamina / Cápsulas Bacterianas / Proteínas de Choque Térmico HSP90 / Citrobacter rodentium / Peptídeos e Proteínas de Sinalização Intracelular / Infecções por Enterobacteriaceae / Proteína Adaptadora de Sinalização NOD2 / Tolerância Imunológica Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilmuramil-Alanil-Isoglutamina / Cápsulas Bacterianas / Proteínas de Choque Térmico HSP90 / Citrobacter rodentium / Peptídeos e Proteínas de Sinalização Intracelular / Infecções por Enterobacteriaceae / Proteína Adaptadora de Sinalização NOD2 / Tolerância Imunológica Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article