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General theory for stochastic admixture graphs and F-statistics.
Soraggi, Samuele; Wiuf, Carsten.
Afiliação
  • Soraggi S; Department of Mathematical Sciences, University of Copenhagen, Denmark.
  • Wiuf C; Department of Mathematical Sciences, University of Copenhagen, Denmark. Electronic address: wiuf@math.ku.dk.
Theor Popul Biol ; 125: 56-66, 2019 02.
Article em En | MEDLINE | ID: mdl-30562538
We provide a general mathematical framework based on the theory of graphical models to study admixture graphs. Admixture graphs are used to describe the ancestral relationships between past and present populations, allowing for population merges and migration events, by means of gene flow. We give various mathematical properties of admixture graphs with particular focus on properties of the so-called F-statistics. Also the Wright-Fisher model is studied and a general expression for the loss of heterozygosity is derived.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processos Estocásticos / Deriva Genética / Genética Populacional Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processos Estocásticos / Deriva Genética / Genética Populacional Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article