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Renal Clearance in Newborns and Infants: Predictive Performance of Population-Based Modeling for Drug Development.
Wang, Jian; Kumar, Shaun S; Sherwin, Catherine M; Ward, Robert; Baer, Gerri; Burckart, Gilbert J; Wang, Yaning; Yao, Lynne P.
Afiliação
  • Wang J; Office of Drug Evaluation IV, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Kumar SS; Department of Pediatrics, Division of Clinical Pharmacology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Sherwin CM; Department of Pediatrics, Division of Clinical Pharmacology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Ward R; Department of Pediatrics, Division of Clinical Pharmacology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Baer G; Office of Pediatric Therapeutics, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Burckart GJ; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Wang Y; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Yao LP; Division of Pediatric and Maternal Health, Office of Drug Evaluation IV, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Clin Pharmacol Ther ; 105(6): 1462-1470, 2019 06.
Article em En | MEDLINE | ID: mdl-30565653

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Taxa de Depuração Metabólica / Desenvolvimento de Medicamentos / Taxa de Filtração Glomerular / Modelos Biológicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Infant / Male / Newborn Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Taxa de Depuração Metabólica / Desenvolvimento de Medicamentos / Taxa de Filtração Glomerular / Modelos Biológicos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Infant / Male / Newborn Idioma: En Ano de publicação: 2019 Tipo de documento: Article