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Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma.
Lapadula, Dominic; Farias, Eduardo; Randolph, Clinita E; Purwin, Timothy J; McGrath, Dougan; Charpentier, Thomas H; Zhang, Lihong; Wu, Shihua; Terai, Mizue; Sato, Takami; Tall, Gregory G; Zhou, Naiming; Wedegaertner, Philip B; Aplin, Andrew E; Aguirre-Ghiso, Julio; Benovic, Jeffrey L.
Afiliação
  • Lapadula D; Department of Biochemistry and Molecular Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Farias E; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Randolph CE; Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Purwin TJ; Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
  • McGrath D; Department of Biochemistry and Molecular Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Charpentier TH; Department of Cancer Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Zhang L; Department of Biochemistry and Molecular Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Wu S; Department of Biochemistry and Molecular Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Terai M; College of Life Sciences, Zhejiang University, Hangzhou, P.R. China.
  • Sato T; College of Life Sciences, Zhejiang University, Hangzhou, P.R. China.
  • Tall GG; Department of Medical Oncology, Sidney Kimmel Medical College, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Zhou N; Department of Medical Oncology, Sidney Kimmel Medical College, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Wedegaertner PB; Department of Pharmacology, University of Michigan Medical Center, Ann Arbor, Michigan.
  • Aplin AE; College of Life Sciences, Zhejiang University, Hangzhou, P.R. China.
  • Aguirre-Ghiso J; Department of Biochemistry and Molecular Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Benovic JL; Department of Cancer Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
Mol Cancer Res ; 17(4): 963-973, 2019 04.
Article em En | MEDLINE | ID: mdl-30567972
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uveais / Subunidades alfa de Proteínas de Ligação ao GTP / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Depsipeptídeos / Melanoma Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uveais / Subunidades alfa de Proteínas de Ligação ao GTP / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Depsipeptídeos / Melanoma Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article