[Research advances in the relationship between iron deficiency and neurodevelopment in preterm infants].
Zhongguo Dang Dai Er Ke Za Zhi
; 20(12): 1070-1074, 2018 Dec.
Article
em Zh
| MEDLINE
| ID: mdl-30573000
ABSTRACT
Iron deficiency (ID) is the most common micronutrient deficiency in children. Due to insufficient iron storage at birth and rapid catch-up growth after birth, preterm infants tend to have a high incidence rate of ID. During the critical period of brain development, ID alters iron-dependent neurometabolism, neurochemistry, neuroanatomy, and gene/protein profiles. This affects the central nervous system and causes the change in neurocognitive and behavioral development. Iron supplementation in infancy cannot reverse neurodevelopmental impairment caused by perinatal ID. The influence of ID on neurodevelopment is time- and region-specific, and in the high-risk population, early diagnosis and optimal iron treatment may help with the recovery of brain function and improve quality of life and long-term prognosis in preterm infants.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Anemia Ferropriva
/
Nascimento Prematuro
Tipo de estudo:
Screening_studies
Limite:
Humans
/
Infant
/
Newborn
Idioma:
Zh
Ano de publicação:
2018
Tipo de documento:
Article