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A 10-Month-Old Infant Presenting With Signs of Precocious Puberty Secondary to a Sclerosing Stromal Tumor of the Ovary in the Absence of Hormonal Elevation.
Squillaro, Anthony I; Zhou, Shengmei; Thomas, Stefanie M; Kim, Eugene S.
Afiliação
  • Squillaro AI; 1 Division of Pediatric Surgery, Children's Hospital Los Angeles, Los Angeles, California.
  • Zhou S; 2 Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California.
  • Thomas SM; 3 Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California.
  • Kim ES; 4 Department of Pediatrics, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Pediatr Dev Pathol ; 22(4): 375-379, 2019.
Article em En | MEDLINE | ID: mdl-30577720
Precocious puberty in an infant is an alarming and infrequent finding, making the differential diagnosis difficult for practitioners. Precocious puberty secondary to a sclerosing stromal tumor (SST) of the ovary is rare. We present a case of a child that began precocious puberty at 3 months of age including development of breast buds, pubic hair, growth spurt, and menarche 5 days prior to presenting to pediatric endocrinology at 10 months. She underwent right salpingo-oophorectomy which demonstrated a soft tissue mass occupying almost the entire ovary with a tan-pink fleshy cut surface. Histological examination confirmed a variant of SST. This case represents an extremely young onset of precocious puberty secondary to a variant of SST without hormonal elevation.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Puberdade Precoce Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Infant Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Puberdade Precoce Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Infant Idioma: En Ano de publicação: 2019 Tipo de documento: Article