Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma.

Hu, Dong Gui; Marri, Shashikanth; McKinnon, Ross A; Mackenzie, Peter I; Meech, Robyn

Hu, Dong Gui; Marri, Shashikanth; McKinnon, Ross A; Mackenzie, Peter I; Meech, Robyn.

Afiliação

Hu DG; Department of Clinical Pharmacology and Flinders Centre for Innovation in Cancer (D.G.H., R.A.M., P.I.M., R.M.), and Department of Molecular Medicine and Pathology (S.M.), Flinders University College of Medicine and Public Health, Flinders Medical Centre, Bedford Park, South Australia, Australia don
Marri S; Department of Clinical Pharmacology and Flinders Centre for Innovation in Cancer (D.G.H., R.A.M., P.I.M., R.M.), and Department of Molecular Medicine and Pathology (S.M.), Flinders University College of Medicine and Public Health, Flinders Medical Centre, Bedford Park, South Australia, Australia.
McKinnon RA; Department of Clinical Pharmacology and Flinders Centre for Innovation in Cancer (D.G.H., R.A.M., P.I.M., R.M.), and Department of Molecular Medicine and Pathology (S.M.), Flinders University College of Medicine and Public Health, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Mackenzie PI; Department of Clinical Pharmacology and Flinders Centre for Innovation in Cancer (D.G.H., R.A.M., P.I.M., R.M.), and Department of Molecular Medicine and Pathology (S.M.), Flinders University College of Medicine and Public Health, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Meech R; Department of Clinical Pharmacology and Flinders Centre for Innovation in Cancer (D.G.H., R.A.M., P.I.M., R.M.), and Department of Molecular Medicine and Pathology (S.M.), Flinders University College of Medicine and Public Health, Flinders Medical Centre, Bedford Park, South Australia, Australia.

J Pharmacol Exp Ther ; 368(3): 363-381, 2019 03.

Article em En | MEDLINE | ID: mdl-30578287

Assuntos

Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Absorção Gastrointestinal/fisiologia; Regulação Neoplásica da Expressão Gênica/fisiologia; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Adolescente; Adulto; Idoso; Idoso de 80 Anos ou mais; Antineoplásicos/metabolismo; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico; Carcinoma Hepatocelular/tratamento farmacológico; Estudos de Coortes; Feminino; Absorção Gastrointestinal/efeitos dos fármacos; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; Neoplasias Hepáticas/tratamento farmacológico; Masculino; Pessoa de Meia-Idade; Distribuição Tecidual; Adulto Jovem

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Carcinoma Hepatocelular / Absorção Gastrointestinal / Neoplasias Hepáticas Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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