Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of <i>o</i>-BMVC Foci.

Tseng, Ting-Yuan; Chu, I-Te; Lin, Shang-Jyun; Li, Jie; Chang, Ta-Chau

Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci.

Tseng, Ting-Yuan; Chu, I-Te; Lin, Shang-Jyun; Li, Jie; Chang, Ta-Chau.

Afiliação

Tseng TY; Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. homeotic@gmail.com.
Chu IT; Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. r04223204@gmail.com.
Lin SJ; Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. john830110@gmail.com.
Li J; Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. julielee0531@gmail.com.
Chang TC; Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan. tcchang@po.iams.sinica.edu.tw.

Molecules ; 24(1)2018 Dec 21.

Article em En | MEDLINE | ID: mdl-30583464

Assuntos

Carbazóis/química; DNA/química; Corantes Fluorescentes/química; Quadruplex G; Microscopia de Fluorescência; Compostos de Piridínio/química; Dicroísmo Circular; DNA/metabolismo; Corantes Fluorescentes/metabolismo; Humanos; Ligantes

Palavras-chave

G-quadruplex; G4 ligands; fluorescence lifetime imaging microscopy; o-BMVC foci

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Piridínio / DNA / Carbazóis / Quadruplex G / Corantes Fluorescentes / Microscopia de Fluorescência Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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