IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses.

Santana Carrero, Rosa M; Beceren-Braun, Figen; Rivas, Sarai C; Hegde, Shweta M; Gangadharan, Achintyan; Plote, Devin; Pham, Gabriel; Anthony, Scott M; Schluns, Kimberly S

Santana Carrero, Rosa M; Beceren-Braun, Figen; Rivas, Sarai C; Hegde, Shweta M; Gangadharan, Achintyan; Plote, Devin; Pham, Gabriel; Anthony, Scott M; Schluns, Kimberly S.

Afiliação

Santana Carrero RM; Immunology Graduate Program, University of Texas (UT) MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77584.
Beceren-Braun F; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX 77584.
Rivas SC; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX 77584.
Hegde SM; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX 77584.
Gangadharan A; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX 77584.
Plote D; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX 77584.
Pham G; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX 77584.
Anthony SM; Cancer Biology Graduate Program, University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77584.
Schluns KS; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX 77584.

Proc Natl Acad Sci U S A ; 116(2): 599-608, 2019 01 08.

Article em En | MEDLINE | ID: mdl-30587590

Assuntos

Regulação Neoplásica da Expressão Gênica/imunologia; Interleucina-15/imunologia; Melanoma/imunologia; Proteínas de Neoplasias/imunologia; Microambiente Tumoral/imunologia; Animais; Linhagem Celular Tumoral; Inflamação/genética; Inflamação/imunologia; Inflamação/patologia; Interleucina-15/genética; Melanoma/genética; Melanoma/patologia; Proteínas de Membrana/genética; Proteínas de Membrana/imunologia; Camundongos; Camundongos Knockout; Proteínas de Neoplasias/genética; Receptores de Interleucina-15/genética; Receptores de Interleucina-15/imunologia; Microambiente Tumoral/genética

Palavras-chave

CD8 T cells; interferons; interleukin 15; myeloid cells; tumors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Interleucina-15 / Microambiente Tumoral / Melanoma / Proteínas de Neoplasias Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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