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Exploiting FAsting-mimicking Diet and MEtformin to Improve the Efficacy of Platinum-pemetrexed Chemotherapy in Advanced LKB1-inactivated Lung Adenocarcinoma: The FAME Trial.
Vernieri, Claudio; Signorelli, Diego; Galli, Giulia; Ganzinelli, Monica; Moro, Massimo; Fabbri, Alessandra; Tamborini, Elena; Marabese, Mirko; Caiola, Elisa; Broggini, Massimo; Hollander, Lital; Gallucci, Rosaria; Vandoni, Giulia; Gavazzi, Cecilia; Triulzi, Tiziana; Colombo, Mario Paolo; Rizzo, Angela Maria; Corsetto, Paola Antonia; Pruneri, Giancarlo; de Braud, Filippo; Sozzi, Gabriella; Torri, Valter; Garassino, Marina Chiara.
Afiliação
  • Vernieri C; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy. Electronic address: claudio.vernieri@istitutotumori.mi.it.
  • Signorelli D; Unit of Thoracic Oncology, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Galli G; Unit of Thoracic Oncology, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Ganzinelli M; Unit of Thoracic Oncology, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Moro M; Tumor Genomics Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Fabbri A; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Tamborini E; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Marabese M; Laboratory of Molecular Pharmacology, Department of Oncology, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Milan, Italy.
  • Caiola E; Laboratory of Molecular Pharmacology, Department of Oncology, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Milan, Italy.
  • Broggini M; Laboratory of Molecular Pharmacology, Department of Oncology, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Milan, Italy.
  • Hollander L; Laboratory of Methodology for Biomedical Research, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Milan, Italy.
  • Gallucci R; Unit of Thoracic Oncology, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Vandoni G; Unit of Nutrition Therapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Gavazzi C; Unit of Nutrition Therapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Triulzi T; Molecular Targeting Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Colombo MP; Department of Experimental Oncology and Molecular Medicine, Molecular Immunology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Rizzo AM; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy.
  • Corsetto PA; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy.
  • Pruneri G; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; School of Medicine, University of Milan, Milan, Italy.
  • de Braud F; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Oncology and Haemato-Oncology Department, University of Milan, Milan, Italy.
  • Sozzi G; Tumor Genomics Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Torri V; Laboratory of Methodology for Biomedical Research, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Milan, Italy.
  • Garassino MC; Unit of Thoracic Oncology, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: marina.garassino@istitutotumori.mi.it.
Clin Lung Cancer ; 20(3): e413-e417, 2019 05.
Article em En | MEDLINE | ID: mdl-30617039
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Jejum / Compostos de Platina / Pemetrexede / Adenocarcinoma de Pulmão / Neoplasias Pulmonares / Metformina Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Jejum / Compostos de Platina / Pemetrexede / Adenocarcinoma de Pulmão / Neoplasias Pulmonares / Metformina Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article