Sulfhydryl treatment of serum or plasma for the reduction of IgM antibodies.
Immunohematology
; 34(4): 135-139, 2018 Dec.
Article
em En
| MEDLINE
| ID: mdl-30624946
ABSTRACT
CONCLUSIONS:
Dithiothreitol (DTT) and 2-mercaptoethanol (2-ME) are sulfhydryl compounds that can be used to treat serum or plasma to denature IgM antibody reactivity. By using sulfhydryl agents, IgG and IgM antibodies can be separated, the relative amount of IgM and IgG antibodies can be determined, and the risk of hemolytic disease of the fetus and newborn can be assessed.
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Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina M
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article