Efficacy of a novel hemostatic adhesive powder in patients with refractory upper gastrointestinal bleeding: a pilot study.
Endoscopy
; 51(5): 458-462, 2019 05.
Article
em En
| MEDLINE
| ID: mdl-30630195
ABSTRACT
BACKGROUND:
A new hemostatic adhesive powder (UI-EWD) has been developed to reduce the high re-bleeding rates associated with the currently available hemostatic powders. The current study aimed to assess the efficacy of UI-EWD as a salvage therapy for the treatment of refractory upper gastrointestinal bleeding (UGIB).METHODS:
A total of 17 consecutive patients who had failed to achieve hemostasis with conventional endoscopic procedures and had undergone treatment with UI-EWD for endoscopic hemostasis in refractory UGIB were prospectively enrolled in the study. We evaluated the success rate of initial hemostasis and rate of re-bleeding within 30 days.RESULTS:
All patients underwent successful UI-EWD application at the bleeding site. Initial hemostasis occurred in 16/17 patients (94â%). Re-bleeding within 30 days occurred in 3/16 patients (19â%) who had achieved initial hemostasis. In the second-look endoscopy after 24 hours, hydrogel from UI-EWD was found attached at the bleeding site in 11/16 patients (69â%).CONCLUSION:
UI-EWD has a high success rate for initial hemostasis in refractory UGIB and shows promising results in the prevention of re-bleeding.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Adesivos
/
Hemostase Endoscópica
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Trato Gastrointestinal Superior
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Tamponamento Interno
/
Hemorragia Gastrointestinal
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article