A novel antimicrobial peptide-derived vehicle for oligodeoxynucleotide delivery to inhibit TNF-&#945; expression.

Hu, Wei-Wen; Huang, Shih-Chun; Jin, Shiow-Lian Catherine

A novel antimicrobial peptide-derived vehicle for oligodeoxynucleotide delivery to inhibit TNF-α expression.

Hu, Wei-Wen; Huang, Shih-Chun; Jin, Shiow-Lian Catherine.

Afiliação

Hu WW; Department of Chemical and Materials Engineering, National Central University, Zhongli District, Taoyuan City, Taiwan; Center for Biocellular Engineering, National Central University, Zhongli District, Taoyuan City, Taiwan. Electronic address: huweiwen@cc.ncu.edu.tw.
Huang SC; Department of Chemical and Materials Engineering, National Central University, Zhongli District, Taoyuan City, Taiwan.
Jin SC; Department of Life Sciences, National Central University, Zhongli District, Taoyuan City, Taiwan.

Int J Pharm ; 558: 63-71, 2019 Mar 10.

Article em En | MEDLINE | ID: mdl-30639220

Assuntos

Peptídeos Catiônicos Antimicrobianos/administração & dosagem; Oligodesoxirribonucleotídeos/administração & dosagem; Fator de Necrose Tumoral alfa/antagonistas & inibidores; Animais; Peptídeos Catiônicos Antimicrobianos/química; Sobrevivência Celular/efeitos dos fármacos; Inativação Gênica; Camundongos; Oligodesoxirribonucleotídeos/química; Células RAW 264.7

Palavras-chave

Gene silence; Indolicidin; Oligodeoxynucleotides; Peptide dimerization; Tumor necrosis factor-α

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligodesoxirribonucleotídeos / Fator de Necrose Tumoral alfa / Peptídeos Catiônicos Antimicrobianos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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