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Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative.
Koruza, Katarina; Mahon, Brian P; Blakeley, Matthew P; Ostermann, Andreas; Schrader, Tobias E; McKenna, Robert; Knecht, Wolfgang; Fisher, S Zoë.
Afiliação
  • Koruza K; Lund Protein Production Platform (LP3) & Department of Biology, Lund University, 223 62 Lund, Sweden.
  • Mahon BP; Department of Molecular Biology, Princeton University, 08544 Princeton, NJ, United States; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, 32610 Gainesville, United States.
  • Blakeley MP; Large-Scale Structures Group, Institut Laue-Langevin, 38042 Grenoble, France.
  • Ostermann A; Heinz Maier-Leibnitz Zentrum (MLZ), Technische Universität München, 85748 Garching, Germany.
  • Schrader TE; Forschungszentrum Jülich GmbH, Jülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ), 85747 Garching, Germany.
  • McKenna R; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, 32610 Gainesville, United States.
  • Knecht W; Lund Protein Production Platform (LP3) & Department of Biology, Lund University, 223 62 Lund, Sweden.
  • Fisher SZ; Lund Protein Production Platform (LP3) & Department of Biology, Lund University, 223 62 Lund, Sweden; Scientific Activities Division, European Spallation Source ERIC (ESS), 221 00 Lund, Sweden. Electronic address: zoe.fisher@esss.se.
J Struct Biol ; 205(2): 147-154, 2019 02 01.
Article em En | MEDLINE | ID: mdl-30639924

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sacarina / Anidrases Carbônicas / Cristalografia por Raios X Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sacarina / Anidrases Carbônicas / Cristalografia por Raios X Idioma: En Ano de publicação: 2019 Tipo de documento: Article