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Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.
Kim, Robbert Q; Geurink, Paul P; Mulder, Monique P C; Fish, Alexander; Ekkebus, Reggy; El Oualid, Farid; van Dijk, Willem J; van Dalen, Duco; Ovaa, Huib; van Ingen, Hugo; Sixma, Titia K.
Afiliação
  • Kim RQ; Division of Biochemistry and Oncode Institute, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.
  • Geurink PP; Division of Cell Biology II, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.
  • Mulder MPC; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Fish A; Division of Cell Biology II, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.
  • Ekkebus R; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • El Oualid F; Division of Biochemistry and Oncode Institute, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.
  • van Dijk WJ; Division of Cell Biology II, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.
  • van Dalen D; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Ovaa H; UbiQ Bio BV, Science Park 408, 1098 XH, Amsterdam, the Netherlands.
  • van Ingen H; Division of Biochemistry and Oncode Institute, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.
  • Sixma TK; Division of Cell Biology II, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.
Nat Commun ; 10(1): 231, 2019 01 16.
Article em En | MEDLINE | ID: mdl-30651545

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Ubiquitina / Peptidase 7 Específica de Ubiquitina Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Ubiquitina / Peptidase 7 Específica de Ubiquitina Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article