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Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemia and hepatic steatosis.
Gwag, Taesik; Meng, Zhaojie; Sui, Yipeng; Helsley, Robert N; Park, Se-Hyung; Wang, Shuxia; Greenberg, Richard N; Zhou, Changcheng.
Afiliação
  • Gwag T; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA.
  • Meng Z; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA.
  • Sui Y; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA.
  • Helsley RN; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA.
  • Park SH; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA.
  • Wang S; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA.
  • Greenberg RN; Department of Medicine, University of Kentucky, Lexington, KY, USA.
  • Zhou C; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA. Electronic address: c.zhou@uky.edu.
J Hepatol ; 70(5): 930-940, 2019 05.
Article em En | MEDLINE | ID: mdl-30677459
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Transcriptase Reversa / Benzoxazinas / Fígado Gorduroso / Receptor de Pregnano X / Hipercolesterolemia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Transcriptase Reversa / Benzoxazinas / Fígado Gorduroso / Receptor de Pregnano X / Hipercolesterolemia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article