Engineered Relaxin as theranostic nanomedicine to diagnose and ameliorate liver cirrhosis.

Nagórniewicz, Beata; Mardhian, Deby F; Booijink, Richell; Storm, Gert; Prakash, Jai; Bansal, Ruchi

Nagórniewicz, Beata; Mardhian, Deby F; Booijink, Richell; Storm, Gert; Prakash, Jai; Bansal, Ruchi.

Afiliação

Nagórniewicz B; Department of Biomaterials Science and Technology, Technical Medical Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Mardhian DF; Department of Biomaterials Science and Technology, Technical Medical Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Booijink R; Department of Biomaterials Science and Technology, Technical Medical Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Storm G; Department of Biomaterials Science and Technology, Technical Medical Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands; Department of Pharmaceutics, Utrecht Institute of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands
Prakash J; Department of Biomaterials Science and Technology, Technical Medical Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Bansal R; Department of Biomaterials Science and Technology, Technical Medical Centre, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands. Electronic address: r.bansal@utwente.nl.

Nanomedicine ; 17: 106-118, 2019 04.

Article em En | MEDLINE | ID: mdl-30677498

Assuntos

Cirrose Hepática/diagnóstico por imagem; Cirrose Hepática/tratamento farmacológico; Nanopartículas de Magnetita/uso terapêutico; Relaxina/uso terapêutico; Animais; Linhagem Celular; Modelos Animais de Doenças; Humanos; Imageamento por Ressonância Magnética; Nanopartículas de Magnetita/química; Masculino; Camundongos Endogâmicos BALB C; Relaxina/análogos & derivados; Relaxina/farmacocinética; Nanomedicina Teranóstica

Palavras-chave

Cirrhosis; Hepatic stellate cells; Nanomedicine; Relaxin; Superparamagnetic iron-oxide nanoparticles (SPIONs); Theranostics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Relaxina / Nanopartículas de Magnetita / Cirrose Hepática Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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