Oral ribavirin for paramyxovirus infection after alemtuzumab-containing reduced-intensity conditioning HCT regimen.
Pediatr Transplant
; 23(2): e13358, 2019 03.
Article
em En
| MEDLINE
| ID: mdl-30687992
ABSTRACT
Aerosolized ribavirin has been used in pediatric immunocompromised patients to treat acute respiratory viral infections, but oral ribavirin may be a less expensive alternative that allows for outpatient therapy. Oral ribavirin has compared favorably to aerosolized ribavirin in adult studies, but data on safety are lacking in pediatric populations. Four cases are described in which oral ribavirin was used to treat viral respiratory infections in recipients of allogeneic hematopoietic stem cell transplants at a Children's Hospital, demonstrating safety and feasibility.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
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Ribavirina
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Infecções por Paramyxoviridae
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Transplante de Células-Tronco Hematopoéticas
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Condicionamento Pré-Transplante
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Alemtuzumab
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Imunossupressores
Limite:
Adult
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Child
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Humans
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Infant
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Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article