Linked Mutations at Adjacent Nucleotides Have Shaped Human Population Differentiation and Protein Evolution.

Prendergast, James G D; Pugh, Carys; Harris, Sarah E; Hume, David A; Deary, Ian J; Beveridge, Allan

Prendergast, James G D; Pugh, Carys; Harris, Sarah E; Hume, David A; Deary, Ian J; Beveridge, Allan.

Afiliação

Prendergast JGD; The Roslin Institute, The University of Edinburgh, Midlothian, United Kingdom.
Pugh C; The Roslin Institute, The University of Edinburgh, Midlothian, United Kingdom.
Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, United Kingdom.
Hume DA; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, United Kingdom.
Deary IJ; Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, United Kingdom.
Beveridge A; Mater Research Institute-University of Queensland, Woolloongabba, Queensland, Australia.

Genome Biol Evol ; 11(3): 759-775, 2019 03 01.

Article em En | MEDLINE | ID: mdl-30689878

Assuntos

Evolução Molecular; Genoma Humano; Mutação; Polimorfismo de Nucleotídeo Único; Códon; Desaminação; Epistasia Genética; Humanos; Seleção Genética

Palavras-chave

DNA repair; MNP; SDM; epistatic selection; human mutation; multinucleotide mutations; multinucleotide polymorphisms; sequential dinucleotide mutations

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Humano / Evolução Molecular / Polimorfismo de Nucleotídeo Único / Mutação Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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