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REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease.
Meyer, Katharina; Feldman, Heather M; Lu, Tao; Drake, Derek; Lim, Elaine T; Ling, King-Hwa; Bishop, Nicholas A; Pan, Ying; Seo, Jinsoo; Lin, Yuan-Ta; Su, Susan C; Church, George M; Tsai, Li-Huei; Yankner, Bruce A.
Afiliação
  • Meyer K; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Feldman HM; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Lu T; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Drake D; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Lim ET; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Ling KH; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
  • Bishop NA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Pan Y; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Seo J; The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Lin YT; The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Su SC; The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Church GM; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Tsai LH; The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Yankner BA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: bruce_yankner@hms.harvard.edu.
Cell Rep ; 26(5): 1112-1127.e9, 2019 01 29.
Article em En | MEDLINE | ID: mdl-30699343
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Redes Reguladoras de Genes / Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer / Neurônios Tipo de estudo: Prognostic_studies Limite: Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Redes Reguladoras de Genes / Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer / Neurônios Tipo de estudo: Prognostic_studies Limite: Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article