A randomized, double-blind, placebo-controlled trial on the efficacy of tranexamic acid combined with rivaroxaban thromboprophylaxis in reducing blood loss after primary cementless total hip arthroplasty.

Clavé, A; Gérard, R; Lacroix, J; Baynat, C; Danguy des Déserts, M; Gatineau, F; Mottier, D

Clavé, A; Gérard, R; Lacroix, J; Baynat, C; Danguy des Déserts, M; Gatineau, F; Mottier, D.

Afiliação

Clavé A; Department of Orthopedics and Traumatology, Brest University Hospital, Brest, France.
Gérard R; Department of Orthopedics and Traumatology, Polyclinique Keraudren, Brest, France.
Lacroix J; Department of Orthopedics and Traumatology, Morlaix General Hospital, Morlaix, France.
Baynat C; Department of Orthopedics and Traumatology, Clermont-Tonnerre Armed Forces Hospital, Brest, France.
Danguy des Déserts M; Department of Anesthesiology, Clermont Tonnerre Military Hospital, Brest, France; Investigation Network on Venous Thromboembolism (F-Crin Network INNOVTE), Saint-Étienne, France.
Gatineau F; Brest University Hospital, University of Western Brittany, Unité de recherche EA 3878 GETBO, Centre d'Investigation Clinique, and Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 1412, Brest, France.
Mottier D; Brest University Hospital, UBO, and EA 3878, CIC INSERM 1412, Brest, France; Investigation Network on Venous Thromboembolism (F-Crin Network INNOVTE), Saint-Étienne, France.

Bone Joint J ; 101-B(2): 207-212, 2019 Feb.

Article em En | MEDLINE | ID: mdl-30700116

Assuntos

Artroplastia de Quadril; Perda Sanguínea Cirúrgica/prevenção & controle; Fármacos Hematológicos/uso terapêutico; Artropatias/cirurgia; Rivaroxabana/uso terapêutico; Ácido Tranexâmico/uso terapêutico; Adulto; Idoso; Idoso de 80 Anos ou mais; Antifibrinolíticos/uso terapêutico; Cimentos Ósseos; Cimentação; Quimioprevenção; Método Duplo-Cego; Inibidores do Fator Xa/uso terapêutico; Feminino; Articulação do Quadril/cirurgia; Humanos; Masculino; Pessoa de Meia-Idade; Estudos Prospectivos; Resultado do Tratamento

Palavras-chave

Blood loss; Cementless; Rivaroxaban; Total hip arthroplasty; Tranexamic acid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Tranexâmico / Perda Sanguínea Cirúrgica / Artroplastia de Quadril / Rivaroxabana / Fármacos Hematológicos / Artropatias Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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