Dopamine transporter forms stable dimers in the live cell plasma membrane in a phosphatidylinositol 4,5-bisphosphate-independent manner.

Das, Anand Kant; Kudlacek, Oliver; Baumgart, Florian; Jaentsch, Kathrin; Stockner, Thomas; Sitte, Harald H; Schütz, Gerhard J

Das, Anand Kant; Kudlacek, Oliver; Baumgart, Florian; Jaentsch, Kathrin; Stockner, Thomas; Sitte, Harald H; Schütz, Gerhard J.

Afiliação

Das AK; From the Institute of Applied Physics, TU Wien, Getreidemarkt 9, A-1060, Vienna and.
Kudlacek O; the Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University Vienna, Waehringerstrasse 13a, A-1090 Vienna, Austria.
Baumgart F; From the Institute of Applied Physics, TU Wien, Getreidemarkt 9, A-1060, Vienna and.
Jaentsch K; the Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University Vienna, Waehringerstrasse 13a, A-1090 Vienna, Austria.
Stockner T; the Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University Vienna, Waehringerstrasse 13a, A-1090 Vienna, Austria.
Sitte HH; the Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University Vienna, Waehringerstrasse 13a, A-1090 Vienna, Austria harald.sitte@meduniwien.ac.at.
Schütz GJ; From the Institute of Applied Physics, TU Wien, Getreidemarkt 9, A-1060, Vienna and schuetz@iap.tuwien.ac.at.

J Biol Chem ; 294(14): 5632-5642, 2019 04 05.

Article em En | MEDLINE | ID: mdl-30705091

Assuntos

Membrana Celular/metabolismo; Proteínas da Membrana Plasmática de Transporte de Dopamina/metabolismo; Fosfatidilinositol 4,5-Difosfato/metabolismo; Multimerização Proteica; Animais; Células CHO; Membrana Celular/genética; Colesterol/genética; Colesterol/metabolismo; Cricetulus; Proteínas da Membrana Plasmática de Transporte de Dopamina/genética; Humanos; Fosfatidilinositol 4,5-Difosfato/genética

Palavras-chave

dimerization; dopamine transporter; inositol phospholipid; membrane protein; neurotransmitter; proteinprotein interaction; single-molecule biophysics; single-molecule brightness analysis; synaptic transmission

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membrana Celular / Fosfatidilinositol 4,5-Difosfato / Proteínas da Membrana Plasmática de Transporte de Dopamina / Multimerização Proteica Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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